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Using two separate drugs to shed pounds can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err to the side of caution and let the FDA do its job and demand some study be done so that the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on his or her medications. Researchers discovered that participants investing in this drug for the year, lost weight within four weeks and have kept the load off during the entire 56 weeks with the study. Contrave is often a combination from the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them more efficient and safer. Combo-pilling may be the newest fad or even better the newest to come under scrutiny and for that reason it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that by right now there are not any long term prescription slimming capsules that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug could also raise blood pressure levels and heartbeat, and must not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heart rate and must not be used in patients with uncontrolled high blood pressure levels, along with by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients for the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. 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